Alan A DiSpirito Selected Research

methanobactin

1/2017	An Aminotransferase Is Responsible for the Deamination of the N-Terminal Leucine and Required for Formation of Oxazolone Ring A in Methanobactin of Methylosinus trichosporium OB3b.
1/2016	Methanobactin reverses acute liver failure in a rat model of Wilson disease.
1/2011	The biogenic methanobactin is an effective chelator for copper in a rat model for Wilson disease.

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Alan A DiSpirito Research Topics

Disease

5	Hepatolenticular Degeneration (Wilson's Disease) 01/2019 - 01/2011
2	Acute Liver Failure (Fulminant Hepatic Failure) 01/2019 - 01/2016
2	Hypoxia (Hypoxemia) 12/2011 - 05/2011
1	Fatty Liver 01/2019
1	Massive Hepatic Necrosis 01/2016
1	Liver Failure 04/2011
1	Body Weight (Weight, Body) 01/2011
1	Hepatitis 01/2011

Drug/Important Bio-Agent (IBA)

5	CopperIBA 01/2019 - 01/2011
3	methanobactinIBA 01/2017 - 01/2011
2	Copper-Transporting ATPasesIBA 01/2016 - 04/2011
2	Hemoglobins (Hemoglobin)IBA 12/2011 - 05/2011
1	NitrogenIBA 12/2011
1	NitritesIBA 05/2011
1	Nitrite Reductases (Nitrite Reductase)IBA 05/2011
1	Chelating AgentsIBA 01/2011

Therapy/Procedure

1	Liver Transplantation 01/2016